Phasix™ Mesh is constructed of monofilament Poly-4-Hydroxybutyrate (P4HB).
Material Structure and Strength
- Fully resorbable monofilament knitted mesh
- Comparable initial strength to traditional polypropylene mesh4
- Gradually degrades over time with minimal resorption throughout the initial 12-26 weeks.5
- Supports repair site up to 12–18 months post implant5
Chronic pain is a serious complication that can occur after groin hernia repair which has been attributed to several mechanisms, including damage to sensory nerves and mesh inguinodynia.6,7 Phasix™ Plug and Patch provide the advantages of a clinically proven technique1 with a fully resorbable mesh to potentially further reduce the risk of chronic pain.
1 Millikan KW., Doolas A. “A Long-Term Evaluation of the Modified Mesh-Plug Hernioplasty in Over 2,000 Patients.” Hernia. 2008 Jun; 12(3): 257-260.
2 Phasix™ Plug and Patch Instructions for Use
3 Martin DP, Williams SF. “Medical Applications of Poly-4-Hydroxybutyrate: A Strong Flexible Absorbable Biomaterial.”
Biochemical Engineering Journal. 2003 (16): 97-105.
4 Benchtop test data on file at C. R. Bard, Inc. Results may not correlate to performance in humans.
5 Preclinical data on file at C. R. Bard, Inc. Results may not correlate to performance in humans.
6 Nienhuijs S et. al.“Chronic pain after mesh repair of inguinal hernia: a systematic review”. Am J Surg. 2007;194(3):394-400.
7 Demierer S, et. al. “The Effect of Polypropylene Mesh on Ilioinguinal Nerve in Open Mesh Repair of Groin Hernia.” Journal of Surgical Research 2006 (131): 175-181.